Substitution at R3 that has a halogen or alkoxy group (74f–74i) brought about a slight rise in mobile potency with the halide analogs (74g–h) showing highest the potency in the group. Further more optimization brought about the discovery of 74i–j, with 74k as quite possibly the most Lively compound while https://indazoleproducts87541.pages10.com/indazole-3-carboxamide-an-overview-66962421