Contrary to the other kinds of hypersensitivity reactions, kind IV reactions are mobile-mediated and antibody-unbiased. These are the next most common kind of hypersensitivity response and typically just take 2 or maybe more days to create. These types of reactions are attributable to the overstimulation of T cells and monocytes/macrophages https://directivepublications.org/journal-of-immunology/