Indeed, TERT phosphorylation has long been proven for being necessary for telomerase activation. b Effect of BETi on telomere regulation. BETi compete with acetylated histones for that binding for the BRD4 bromodomains releasing BRD4 from limited telomere, destabilizing telomere protection elaborate Group and minimizing Telomerase activity. The progressive shortening of https://-jq-1inhibitionofbrd403467.blogcudinti.com/31937751/not-known-details-about-jq-1-mechanism-of-action