Finally, clonidine enhances neuraxial opioids and, in combination with fentanyl, interacts in an additive manner, which could reduce the dose of each ingredient by 60% for postoperative analgesia. Clonidine treats large blood pressure level by stimulating αtwo receptors during the brainstem, which decreases peripheral vascular resistance, lowering blood pressure. https://stephenp469rni7.wikilinksnews.com/user