During the late eighties William Devane and Allyn Howlett initial postulated the existence of cannabinoid receptors by displaying how artificial molecules intended to mimic the steps of Δ9-THC were in the position to bind a selective site in brain membranes, Therefore inhibiting the intracellular synthesis of cyclic adenosine monophosphate (cAMP) https://augustuclrx.blognody.com/33997820/thc-concentrates-fundamentals-explained